The strike, carried out in the Derdghaiya area of southern Lebanon, was led by the 91st Division.
Israeli officials are holding discussions on whether to respond to the recent missiles launched from Yemen.
The announcement showed the IDF keeping the newly increased pressure on Hamas since Israel renewed hostilities at 2:10 a.m. Tuesday.
The IDF said it "did not strike a UN compound in Deir el Balah," and called on media outlets to act with caution regarding unverified reports.
Sources to 'Post': UN officials harmed by clearing landmines, not by Israeli airstrike • IDF strikes Hamas terrorists in Gaza in restrained second round
Is the change in the White House the primary difference?
"Israel allowed Qatar to transfer 978 fuel tankers into Gaza, containing tens of millions of liters worth over NIS 1 billion to Hamas," he noted.
As mediators blitz through attempt to bring about an agreement for the release of additional hostages, the question remains: If this fails, what comes next?
His comments came before Israel began renewed strikes on targets in Gaza later on Monday night.
"The prime minister and cabinet chose knowingly to sacrifice the hostages in the [Gaza] Strip," said the brother of released hostage Tal Shoham.