The Islamic Republic is currently researching security breaches, with sources claiming Qaani and his team were under isolation.
Our fingers are on the trigger right now in order to turn the enemy into dust if it makes the smallest mistake," the IRGC commander added.
Prime Minister Benjamin Netanyahu and Defense Minister Yoav Gallant have both presented removing the Iranian nuclear threat.
Biden and other US officials have said that strikes on nuclear facilities would be ineffective and "plunge the region into a full-scale war."
Social media users said they heard the sound of an explosion at around 2 o’clock on Tuesday morning in Isfahan.
Qaani traveled to Lebanon after the killing last month of Hezbollah leader Sayyed Hassan Nasrallah in an Israeli airstrike.
Qaani may have been wounded in the strike that targeted Hassan Nasrallah's presumed successor, according to N12.
Hezbollah has refrained from officially appointing a successor to Nasrallah, possibly to avoid making his replacement a target for an Israeli assassination, they said.
"We do not now see other aerial threats from Iran...So we issued instructions to [the Israeli populace] leave safety areas."
"The US is complicit in all of these crimes and...has to accept the repercussions," Iran's parliament speaker Mohammad Baqer Qalibaf said.