The suspected terrorist was shot at the scene and police are investigating the incident.
Israeli media reported that security forces with water cannons were en route to the Ayalon highway to disperse the crowds.
See no evil: In what universe is there a moral equivalency between ramming a vehicle into people standing at a bus stop and a young person losing his life in a crossfire with terrorists?
The truck driver also struck three men on mopeds who suffered minor injuries, WABC-TV reported.
Politicians around the world and foreign ambassadors in Israel condemned the terror attack in Jerusalem on Friday.
The National Security Minister announced a major operation in east Jerusalem to battle terrorism.
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