The hypersonic missile is claimed to have the capacity to bypass the most advanced anti-ballistic missile systems of the United States and Israel.
Khamenei made his latest comments while attending an exhibition showcasing the "latest achievements" of the Islamic Revolutionary Guard Corps' Aerospace Force, including the Fattah 2.
Iran's Khamenei has taken to social media in the past to attack Israel, the United States, and other parties Iran sees as adversarial.
"The bombings on Gaza must stop immediately ... the path of oil and food exports to the Zionist regime should be stopped," Iran's Supreme Leader Ayatollah Ali Khamenei said in a speech.
Addressing this turbulent situation requires careful consideration of regional dynamics, diplomatic efforts and an understanding of the shared goals and motivations that drive these terrorist groups.
"The Zionist regime is dying," said Iran's Ayatollah Ali Khamenei in a post on X.
Israel and the US have repeatedly called for their allies to join in their recognition of the IRGC as a terrorist entity, though many countries remain hesitant to do so.
The new security chief has a background in the IRGC navy and also in conducting operations near Bandar Abbas.
The poisonings began in November in the holy Shi'ite Muslim city of Qom and spread to 25 of Iran's 31 provinces, prompting some parents to take children out of school and protest.
This decision by Iran’s supreme leader Ayatollah Ali Khamenei was announced on Sunday and was on the front page of pro-regime media.