Meanwhile, Trump wrote on social media that Israel and Iran should and will make a deal soon and called to make the Middle East great again.
Israelis on social media reported hearing explosions, particularly in the Tel Aviv and Haifa areas.
Christodoulides said Iran had asked Cyprus to convey 'some messages' to Israel but he did not say who specifically the messages were from or what they said.
Israel conveyed a message in the last 24 hours to Iran that it would strike strategic infrastructure across the country if the Islamic Republic targets civilian population centers.
He warned that proximity to the buildings endangered their lives.
Israel also targets the headquarters of Iran's Defense Ministry • Defense Minister Israel Katz: "Tehran is ablaze"
Israel has taken a substantial bite out of Tehran's nuclear program, but it is far from down for the count.
The jets struck the site, containing Surface-to-Surface Missiles and Cruise Missiles, after receiving guidance from the Intelligence Directorate.
Defrin "could not disclose" whether Khamenei is one of Israel's strike targets when asked by a reporter.
Ali Shamkhani, top adviser to Iranian Supreme Leader Ali Khamenei, was killed in Israeli strikes on a "sensitive military center" in western Iran, local media said.
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